Filtered By:
Therapy: Pain Management

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 26596 results found since Jan 2013.

Pharmacokinetics of flunixin meglumine in mature swine after intravenous, intramuscular and oral administration
Conclusions: The results of the present study suggest that FM oral administration is not the most effective administration route for mature swine when compared to IV and IM. Lower F and Cmax of PO-FM in comparison to IM-FM suggest that PO-FM is less likely to be an effective therapeutic administration route.
Source: BMC Veterinary Research - Latest articles - August 13, 2013 Category: Veterinary Research Authors: Monique Pairis-GarciaLocke KarrikerAnna JohnsonButch KukanichLarry WulfSuzanne SanderSuzanne MillmanKenneth StalderJohann Coetzee Source Type: research

Feasibility Study on MR-Guided High-Intensity Focused Ultrasound Ablation of Sciatic Nerve in a Swine Model: Preliminary Results
Conclusion The acute pilot study in swine demonstrated the feasibility of a noninvasive neurolysis of the sciatic nerve using a clinical MRgHIFU system. Results revealed that acute HIFU nerve lesions were detectable on CE MRI, gross pathology, and histology.
Source: CardioVascular and Interventional Radiology - June 4, 2015 Category: Radiology Source Type: research

On RSS Readers, Divorce and Marriage
In just a few days, Google Reader will be history.  I've used it to create over 18,000 Tweets, so yes, I will miss Google Reader.  The end has pushed me into a divorce (or maybe it's just a separation?!) — from Google.  I describe my Google divorce as kind of like when a married couple with children decide to separate … they still have to see their exes for the sake of the kids (and I still have my blogs with Google's Blogger, for now anyway), and it may be a cordial, but not quite blissful separation, but is still necessary.A number of my fellow diabetes blogging peers have already migrated from Google'...
Source: Scott's Web Log - June 28, 2013 Category: Diabetes Authors: Scott S Source Type: blogs

Analysis of google trends and search results for ophthalmic symptoms of monkeypox
ConclusionSearch interest in monkeypox ophthalmic symptoms corresponds with geographic and temporal trends, i.e., timing and location of the first reported non-endemic cases and WHO announcement. Although ophthalmic symptoms are not as widely searched currently, inclusion in public health messaging is key for diagnosis, appropriate management, and reduction of further transmission.
Source: International Ophthalmology - April 18, 2023 Category: Opthalmology Source Type: research

What People Search for When Browsing "Doctor Google." An Analysis of Search Trends in Italy after the Law on Pain.
Authors: Miceli L, Bednarova R, Bednarova I, Rizzardo A, Cobianchi L, Dal Mas F, Biancuzzi H, Bove T, Dal Moro F, Zattoni F Abstract Italy adopted a law on chronic pain in March 2010, which focused on detection and management of this symptom, that affects approximately 25% of the population. The aim of this study is to analyze the interest of the Italian population in palliative care and chronic pain and to understand whether the Law 38/2010 made an impact on the internet search on chronic pain. Five research parameters were included using Google Trends (chronic pain, anti-inflammatory drugs, opioids, fibromyalgia,...
Source: Journal of Pain and Palliative Care Pharmacotherapy - February 13, 2021 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Psychosocial Effects of Cancer Cachexia: A Systematic Literature Search and Qualitative Analysis
Conclusion: The concept of psychosocial effects in cancer cachexia has the potential to sensitize health care professionals to cachexia-related problems and inform their clinical management of the condition.
Source: Journal of Pain and Symptom Management - November 19, 2012 Category: Palliative Care Authors: Rolf Oberholzer, Jane B. Hopkinson, Kim Baumann, Aurelius Omlin, Stein Kaasa, Kenneth C. Fearon, Florian Strasser Tags: Review Articles Source Type: research

Neonatal pain management: still in search for the Holy Grail.
Authors: Allegaert K, van den Anker JN Abstract Inadequate pain management but also inappropriate use of analgesics in early infancy has negative effects on neurodevelopmental outcome. As a consequence, neonatal pain management is still in search for the Holy Grail. At best, effective pain management is based on prevention, assessment, and treatment followed by a re-assessment of the pain to determine if additional treatment is still necessary. Unfortunately, epidemiological observations suggest that neonates are undergoing painful procedures very frequently, unveiling the need for effective preventive, non-pharmac...
Source: International Journal of Clinical Pharmacology and Therapeutics - April 20, 2016 Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research

Pharmacological treatment of neonatal pain: In search of a new equipoise
Summary: Inadequate management of pain in early human life contributes to impaired neurodevelopmental outcome and alters pain thresholds, pain or stress-related behavior and physiological responses. However, there are also emerging animal experimental data on the impact of exposure to analgo-sedatives on the incidence and extent of neuro-apoptosis. Since this association has also been suggested in humans, the pharmacological treatment of neonatal pain is in search of a new equipoise since these ‘conflicting’ observations are the main drivers to further reconsider our current treatment regimens. This review focuses on n...
Source: Seminars in Fetal and Neonatal Medicine - October 29, 2012 Category: Perinatology & Neonatology Authors: Karel Allegaert, Dick Tibboel, John van den Anker Source Type: research

The search for novel analgesics: targets and mechanisms.
Authors: Yaksh TL, Woller SA, Ramachandran R, Sorkin LS Abstract The management of the pain state is of great therapeutic relevance to virtually every medical specialty. Failure to manage its expression has deleterious consequence to the well-being of the organism. An understanding of the complex biology of the mechanisms underlying the processing of nociceptive information provides an important pathway towards development of novel and robust therapeutics. Importantly, preclinical models have been of considerable use in determining the linkage between mechanism and the associated behaviorally defined pain state. Th...
Source: F1000 Medicine Reports - June 23, 2015 Category: Biomedical Science Tags: F1000Prime Rep Source Type: research

Tuberous Sclerosis Complex: One Woman's Search for Renal-Preserving Therapy.
Abstract Everolimus was very effective in the treatment of Anne, a patient with TSC and renal angiomyolipomas. Anne's renal tumors continue to shrink in size, with a decrease of more than 50% achieved to date, and her GFR remains in the normal range. She no longer experiences chronic back pain due to kidney tumors and is not taking pain medications. She is active and able to exercise daily, and her blood pressure remains within normal limits. Usually diagnosed in childhood, TSC requires life-long management. Patients can have many manifestations of the disease, and nurses need to be made aware of them because they...
Source: Nephrology Nursing Journal - September 1, 2015 Category: Nursing Authors: Coombs EJ Tags: Nephrol Nurs J Source Type: research

Kienbock's Disease: Treatment Options - A Search for the Apt!
J Hand Surg Asian Pac Vol. 2021 Jun;26(2):142-151. doi: 10.1142/S2424835521400038.ABSTRACTKienbock's disease remains a condition of uncertain etiology and our understanding about the pathogenesis is still evolving. However, a lack of consensus on the treatment is the most striking as there are wide array of treatment options described ranging from 'doing nothing' to a free vascularized bone graft reconstruction of the lunate. Furthermore, most treatment modalities report equivalent success rate but cumulative evidence is lacking. This 'black hole' in the literature presents difficulties to surgeons treating the condition a...
Source: Hand Surgery - April 30, 2021 Category: Surgery Authors: Praveen Bhardwaj Vigneswaran Varadharajan Neeraj Godora S Raja Sabapathy Source Type: research

Spiritual Pain: A Symptom in Search of a  Clinical Definition
AbstractWe conducted a literature search to identify and compare definitions of the experiential dimension of spiritual pain. Key databases were searched, up to the year 2021 inclusive, for papers with a definition of “spiritual” or “existential” pain/distress in a clinical setting. Of 144 hits, seven papers provided theoretical definitions/descriptions; none incorporated clinical observations or underlying pathophysiological constructs. Based on these findings, we propose a new definition for “spiritua l pain” as a “self-identified experience of personal discomfort, or actual or potential harm, triggered by ...
Source: Journal of Religion and Health - September 9, 2022 Category: Medical Ethics Source Type: research

Searching for Smaug
“My armour is like tenfold shields, my teeth are swords, my claws spears, the shock of my tail is a thunderbolt, my wings a hurricane, and my breath death!“ Smaug, the most powerful, the most cunning, and some would even say the greatest, dragon of the Third Age, had a story steeped in mystery.  By the time an unexpected journey began, Smaug had not been seen for 150 years, but legend had it that he had laid waste to the Lonely Mountain in Erebor, and was feared as a ruthless killer. The obvious questions that ensue from this frightening tale are: Does Smaug really exist, or is he some terrifying myth? If ...
Source: Life in the Fast Lane - April 3, 2013 Category: Emergency Medicine Doctors Authors: Michelle Johnston Tags: Education eLearning Emergency Medicine Featured Respiratory pneumothorax smaug tension tension pneumo thoracostomy Source Type: blogs